According to the video, the St. Louis brewery produces 14.5 million barrels a year, making it the largest brewery in North America. “If you are a home brewer, you're weighing in pounds,” Joel Boissell, brewmaster at the St. Louis brewery told CNN Money. Inside Budweiser's Largest BreweryManufacturing Business Technology Budweiser brewer earnings fall on taxes, financingAsbury Park Press all 36 news articles »